/ Side by side

PT-141 vs Melanotan II

A neutral, side-by-side look at PT-141 and Melanotan II: what each one is, its class, half-life, storage, and the public sources behind it. Educational reference only, not medical advice, dosing, or a recommendation to use either compound.

AttributePT-141Melanotan II
CategorySexual / HormonalSexual / Hormonal
Half-life~2.7 h terminal~1 h, subcutaneous
Common vial10 mg10 mg
ReferenceVerifiedVerified

What is PT-141?

A synthetic melanocortin receptor agonist that acts on central pathways involved in sexual arousal. FDA-approved as Vyleesi and studied for hypoactive sexual desire disorder in premenopausal women.

Sources

  • FDA label: Vyleesi (2019)
Read the PT-141 profile →

What is Melanotan II?

A synthetic cyclic analog of alpha-melanocyte-stimulating hormone acting as a non-selective melanocortin receptor agonist. Studied in relation to skin pigmentation and, via MC4R activation, sexual arousal. Not FDA-approved.

Sources

  • ScienceDirect Topics: Melanotan II
  • Peer-reviewed melanocortin pharmacology
Read the Melanotan II profile →

Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.