/ Side by side
MK-677 vs Ipamorelin
A neutral, side-by-side look at MK-677 and Ipamorelin: what each one is, its class, half-life, storage, and the public sources behind it. Educational reference only, not medical advice, dosing, or a recommendation to use either compound.
MK-677
Ibutamoren · Nutrobal
Full profile →Ipamorelin
Full profile →| Attribute | MK-677 | Ipamorelin |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Half-life | ~24 h, oral | ~2 h, subcutaneous |
| Common vial | 10, 25 mg | 5, 10 mg |
| Reference | Verified | Verified |
What is MK-677?
An orally active, non-peptide ghrelin-receptor (GHS-R1a) agonist that produces sustained elevation of growth hormone and IGF-1. Its long half-life supports once-daily oral use.
Sources
- Chapman et al., J Clin Endocrinol Metab 1996
What is Ipamorelin?
A selective ghrelin/growth-hormone-secretagogue receptor (GHS-R1a) agonist pentapeptide that stimulates pituitary growth hormone release with minimal effect on cortisol or prolactin.
Sources
- Raun et al., Eur J Endocrinol 1998
- Ishida et al. 2020 (GHS review)
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.