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Semaglutide vs Cagrilintide

A neutral, side-by-side look at Semaglutide and Cagrilintide: what each one is, its class, half-life, storage, and the public sources behind it. Educational reference only, not medical advice, dosing, or a recommendation to use either compound.

AttributeSemaglutideCagrilintide
CategoryGLP-1 / MetabolicGLP-1 / Metabolic
Half-life~1 week~7 days
Common vial2, 3, 5, 10 mg5, 10 mg
ReferenceVerifiedVerified

What is Semaglutide?

A GLP-1 receptor agonist, acylated for albumin binding and DPP-4 resistance, studied for glycemic control in type 2 diabetes and for weight management. Its long half-life supports once-weekly administration.

Sources

  • FDA label: Ozempic, subcutaneous (NDA 209637)
  • FDA label: Wegovy, subcutaneous (NDA 215256)
  • FDA label: Rybelsus, oral (NDA 213051)
Read the Semaglutide profile →

What is Cagrilintide?

A long-acting acylated amylin analog engineered to resist aggregation and bind albumin, studied in trials for appetite regulation and weight management, often alongside a GLP-1 agonist. Investigational.

Sources

  • Kruse et al., J Med Chem 2021
  • Phase 1 PK (once-weekly dosing)
Read the Cagrilintide profile →

Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.