Growth Hormone Peptides
Growth-hormone compounds are secretagogues and growth-hormone-releasing-hormone (GHRH) analogs studied for how they interact with the pituitary and the growth-hormone and IGF-1 axis. They act on the body to release its own growth hormone rather than supplying the hormone directly, and they differ mainly in selectivity and half-life.
8 compounds
Ipamorelin
A selective ghrelin/growth-hormone-secretagogue receptor (GHS-R1a) agonist pentapeptide that stimulates pituitary growth hormone release with minimal effect on cortisol or prolactin.
CJC-1295
with DAC · mod GRF 1-29
A synthetic growth-hormone-releasing hormone (GHRH) analog that binds pituitary GHRH receptors to stimulate growth hormone secretion. The DAC (drug affinity complex) version binds albumin for a much longer half-life than the unmodified peptide.
Sermorelin
Geref · GHRH 1-29
A synthetic peptide corresponding to the first 29 amino acids of growth-hormone-releasing hormone that binds pituitary GHRH receptors to stimulate endogenous growth hormone secretion. Previously marketed (Geref) and used in diagnostic testing.
MK-677
Ibutamoren · Nutrobal
An orally active, non-peptide ghrelin-receptor (GHS-R1a) agonist that produces sustained elevation of growth hormone and IGF-1. Its long half-life supports once-daily oral use.
GHRP-2
Pralmorelin
A synthetic ghrelin-mimetic hexapeptide (pralmorelin) that activates the growth-hormone-secretagogue receptor (GHS-R1a) to stimulate pituitary growth hormone release; used diagnostically in some countries.
GHRP-6
The original synthetic ghrelin-mimetic hexapeptide that activates the growth-hormone-secretagogue receptor (GHS-R1a) to stimulate pituitary growth hormone release; it also strongly stimulates appetite.
Hexarelin
A synthetic ghrelin-mimetic hexapeptide and potent GHS-R1a agonist, structurally related to GHRP-6, that stimulates pituitary growth hormone release; it also interacts with cardiac CD36 receptors in research settings.
MGF
PEG-MGF · Mechano Growth Factor · IGF-1Ec
Mechano Growth Factor, a splice variant of insulin-like growth factor 1 (IGF-1Ec in humans) expressed in mechanically loaded or damaged muscle. Its unique C-terminal E-domain peptide is studied for satellite-cell activation and muscle repair. PEG-MGF is a pegylated synthetic version of that peptide. Research material not approved for human use.
Browse other classes
Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.