Sexual & Hormonal Peptides
Sexual and hormonal compounds include melanocortin receptor agonists and peptides that act on the hypothalamic-pituitary-gonadal axis, studied in reproductive and sexual-health research. The group spans FDA-approved products and research-only materials, so handling and regulatory status vary widely from entry to entry.
6 compounds
PT-141
Bremelanotide · Vyleesi
A synthetic melanocortin receptor agonist that acts on central pathways involved in sexual arousal. FDA-approved as Vyleesi and studied for hypoactive sexual desire disorder in premenopausal women.
Melanotan II
MT-2 · MT2
A synthetic cyclic analog of alpha-melanocyte-stimulating hormone acting as a non-selective melanocortin receptor agonist. Studied in relation to skin pigmentation and, via MC4R activation, sexual arousal. Not FDA-approved.
Kisspeptin
Kisspeptin-10 · Kisspeptin-54
Endogenous neuropeptides (KISS1 products) that agonize the KISS1R/GPR54 receptor on hypothalamic GnRH neurons, stimulating pulsatile GnRH release and downstream LH and FSH secretion. Studied in reproductive neuroendocrinology and fertility research.
Gonadorelin
GnRH · Factrel
A synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH) that binds pituitary GnRH receptors to stimulate release of LH and FSH. Pulsatile use stimulates them; continuous use suppresses them.
HCG
Human Chorionic Gonadotropin · Novarel
A glycoprotein hormone that acts as a functional analog of luteinizing hormone, binding LH/CG receptors to stimulate gonadal steroidogenesis. FDA-approved for uses including ovulation induction and certain hypogonadotropic conditions. Dosed in international units.
Melanotan I
Afamelanotide · Scenesse · MT-1 · NDP-MSH
A synthetic linear analog of alpha-melanocyte-stimulating hormone ([Nle4-D-Phe7]-alpha-MSH) that acts as a melanocortin (MC1R-preferring) agonist to stimulate eumelanin synthesis. Marketed as afamelanotide (Scenesse), an FDA-approved subcutaneous implant for photoprotection in erythropoietic protoporphyria.
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Educational reference only, compiled from public sources. Not medical advice, diagnosis, treatment, or a dosing recommendation, and not a recommendation to use any compound. Many compounds listed are research materials not approved for human use. Consult a qualified professional.